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Tenivastatin-d<sub>6</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119695AS

    Tenivastatin-d<sub>6sub> ammonium

    Isotope-Labeled Compounds Endogenous Metabolite Cardiovascular Disease
    Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1].
    Simvastatin acid-d6 ammonium

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